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F-star

F-star is an innovation-focused biotech company developing next-generation multispecific antibody therapeutics to transform the lives of patients with cancer and other serious diseases.

BiotechnologyBiopharmaceuticalsImmuno-oncologyTherapeuticsCancer researchHealthcarePharmaceuticals
Founded: 2011

About

F-star is a biotech company dedicated to developing novel, next-generation multispecific antibody therapeutics, focusing on cancer and other serious diseases. Their proprietary, clinically validated antibody platform enables the creation of tetravalent (2+2) bispecific antibodies that bind multiple antigens, designed for potent and safe immune system activation. F-star leverages its Fcab® and mAb2® platforms for the rapid discovery and development of differentiated drugs, aiming to address patients with significant unmet medical needs. Their approach offers robust manufacturing, strong safety, and enhanced biological potency. F-star's mission is to deliver life-extending and quality-of-life-improving treatments, particularly for patients with advanced cancer who have limited options.

Products & Services

  • Development of next-generation multispecific (tetravalent bispecific) antibody therapeutics
  • Fcab® and mAb2® technology platforms for drug discovery
  • Immunotherapies for cancer
  • Clinical-stage drug candidates including FS118 (anti-LAG-3/PD-L1) and FS222 (CD137/PD-L1 tetravalent bispecific antibody)
  • Preclinical and clinical drug candidate pipeline
  • Scientific research collaborations and licensing of antibody technologies

Use Cases & Case Studies

  • FS118 (anti-LAG-3/PD-L1 tetravalent bispecific antibody) investigated in clinical trials for advanced cancer and PD-L1 resistance
  • FS222 (CD137/PD-L1 bispecific antibody) evaluated in clinical trials for immunotherapy in colorectal and other cancers

Partnerships & Collaborations

  • Merck KGaA, Darmstadt, Germany
  • Denali Therapeutics
  • Janssen (Johnson & Johnson)
  • Takeda

Awards & Recognition

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Contact Information

www.f-star.com
Cambridge
GBR

Certifications & Compliance

  • GDPR compliance (General Data Protection Regulation)