New polymer comprising two substances that bind to amyloid-beta-oligomers, useful for treating Alzheimer's disease, Parkinson's disease, Creutzfeldt Jakob disease or diabetes

Publication: DE102012102998A1
Published: 2013-10-10
Family Size: 2
Granted: Yes (1/2)

Simple SummaryContent extracted from patent full text and abstract with AI.

This invention is a new type of polymer that includes at least two different components designed to bind specifically to amyloid-beta oligomers, which are protein aggregates implicated in diseases like Alzheimer's, Parkinson's, Creutzfeldt Jakob disease, and diabetes. The polymer can be incorporated into kits and sensors, offering both therapeutic and diagnostic applications.

Use CasesContent extracted from patent full text and abstract with AI.

  • Therapeutic agent for treating Alzheimer's disease by inhibiting amyloid-beta aggregation
  • Treatment for Parkinson's disease and other neurodegenerative disorders involving amyloid aggregates
  • Diagnostic sensor to detect amyloid-beta oligomers in biological samples
  • Nootropic applications to improve cognitive function by targeting harmful protein aggregates
  • Kit for clinical or laboratory use to screen or monitor amyloid-related diseases
  • Potential adjunct therapy for diabetes if amyloid-related mechanisms are implicated

BenefitsContent extracted from patent full text and abstract with AI.

  • Selective binding to disease-causing amyloid-beta oligomers, potentially reducing toxicity
  • Versatile use in both treatment (as a therapeutic) and detection (as a sensor)
  • May offer neuroprotection and cognitive improvement for patients
  • Could contribute to early and accurate diagnosis of neurodegenerative diseases
  • Potential to address multiple diseases sharing amyloid-beta aggregation as a cause
  • Novel polymer structure may be more effective or safer than existing therapies

Technical Classifications (CPCs)

Main Classifications

Chemistry & Materials Science

Physics & Measurement

Sub Classifications

Measuring & Testing

Organic Chemistry

CPC Codes

C07K7/08C07K14/4711G01N33/6896

Inventors & Applicants

Applicants

Forschungszentrum Juelich Gmbh

Patent Abstract

Polymer comprising at least two substances (monomers) that bind to amyloid-beta -oligomers is new. Independent claims are included for: (1) a Kit comprising the polymer; (2) a sensor comprising the polymer; and (3) producing the polymers. ACTIVITY : Neuroprotective; Nootropic; Antiparkinsonian; Antidiabetic. MECHANISM OF ACTION : Amyloid-beta inhibitor.

Key Information

Publication No.

DE102012102998A1

Family ID

49209829

Publication Date

2013-10-10

Application No.

DE102012102998A

Application Date

2012-04-05

Priority Date

2012-04-05

Granted

Yes (1/2)

Possible Cooperation

For further information please contact the transfer office.