Use of ionic liquid comprising e.g. pyridinium cation for increasing the half-life of cofactors e.g. NADPH and NADH

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent describes the use of ionic liquids, such as those containing pyridinium cations, to prolong the stability and functional half-life of essential biological cofactors like NADPH and NADH. It further covers sensors that utilize an immobilized enzyme and a cofactor, stabilized with the ionic liquid, to enhance performance.

Use CasesContent extracted from patent full text and abstract with AI.

• Biosensors that require long-lasting enzyme activity for medical diagnostics or environmental monitoring.
• Industrial biocatalytic processes where cofactors are required for enzymatic reactions, improving efficiency and reducing costs.
• Development of lab-on-a-chip devices with longer operational life due to stabilized enzymes and cofactors.
• Pharmaceutical manufacturing processes using enzyme-driven synthesis steps, benefitting from enhanced cofactor stability.

BenefitsContent extracted from patent full text and abstract with AI.

• Prolongs the active life of important cofactors (NADPH/NADH), reducing the need for frequent replacement and lowering costs.
• Improves the performance and lifespan of biosensors and enzymatic devices.
• Enables more efficient and stable industrial biocatalytic processes.
• Can contribute to more robust and reliable biochemical assays and diagnostic tools.

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Inventors & Applicants

Patent Abstract

Use of ionic liquid to increase the half-life of cofactors, is claimed. An independent claim is also included for a sensor comprising a substrate, an immobilized enzyme and a cofactor, that is charged with the ionic liquid.