Biomarker for the Diagnosis of Sleep Disorders

Simple SummaryContent extracted from patent full text and abstract with AI.

This invention relates to the identification and use of specific blood-based biomarkers for diagnosing sleep disorders. By measuring the concentration of at least two (and preferably more) biomarkers such as pyridoxine (vitamin B6), N-acetyl glutamine, glycocholate, 3-hydroxyphenyl acetate, and others using quantitative NMR metabolomics, clinicians can quickly and non-invasively determine if a patient has or is at risk of a sleep disorder. The invention also covers processes for monitoring therapy effectiveness, computer-implemented diagnostic systems, and software to automate analysis and alert users to abnormalities.

Use CasesContent extracted from patent full text and abstract with AI.

• Rapid blood-based diagnostic tests for sleep disorders in clinical and outpatient settings.
• Screening shift workers, transportation professionals, or people in high-risk industries for sleep-related impairments.
• Monitoring patient response to therapies for sleep disorders.
• Integrating biomarker testing into workplace health programs to identify employees at risk of fatigue-related errors.
• Automated software solutions for laboratories and hospitals to process sleep disorder diagnostics data.
• Personalized medicine approaches adjusting treatment based on biomarker levels.

BenefitsContent extracted from patent full text and abstract with AI.

• Provides a much faster diagnosis of sleep disorders compared to traditional overnight sleep studies.
• Non-invasive and convenient, requiring only a blood sample.
• Can identify individuals at risk before severe symptoms or accidents occur.
• Enables objective, quantifiable monitoring of therapy effectiveness over time.
• Reduces burden on sleep clinics and minimizes wait times for patients.
• Supports automation, standardization, and potentially scalable analysis with computer/software integration.
• Applicable in various settings, including occupational health, clinical diagnostics, and research.
• Facilitates early intervention and risk management, potentially preventing accidents and health deterioration.

Technical Classifications (CPCs)

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Patent Abstract

The present invention is directed to biomarkers indicative of sleep disorder, processes for diagnosing sleep disorder as well as further systems and computer related implementations in this regard.