Method for creating C-11 and target body

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This patent describes a method and specialized container (target body) for producing the radioactive isotope carbon-11 (C-11), used mainly in medical imaging. The invention involves coating the side of the target body facing the target with a material that acts as a diffusion barrier to carbon, such as a precious metal (e.g., gold) or aluminum nitride. This barrier prevents contamination by stable carbon-12 atoms from the container material, thereby significantly increasing the purity and specific radioactivity of the produced C-11, which is critical for high-quality radiopharmaceuticals.

Use CasesContent extracted from patent full text and abstract with AI.

• Production of high-specific-activity C-11 for positron emission tomography (PET) radiopharmaceuticals.
• Manufacture of radiotracers for brain and neurological research.
• Preparation of radioactive markers for metabolic studies in medicine and biology.
• Use in research cyclotrons at hospitals and radiochemistry labs to improve quality of PET isotope production.

BenefitsContent extracted from patent full text and abstract with AI.

• Substantially higher purity and specific radioactive activity of C-11, resulting in more effective and reliable radiotracers.
• Reduction in contamination from stable carbon-12, leading to more accurate clinical and research imaging results.
• Ability to use less radiotracer while achieving the same effect, thus reducing potential biological side effects and cost.
• Enhanced longevity and usability of radiopharmaceuticals due to higher initial activity.
• Applicable to existing target body materials (e.g., aluminum, steel, iron), making it a versatile and cost-effective improvement for medical isotope production.

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Patent Abstract

Carbon-11 production involves bombarding target in a target body. A side of the target body is coated partially with a material, which represents a diffusion barrier for carbon. The carbon is placed in the material of the target body (1) or totally made of this material or a sleeve made of this material is placed at side of the target body. The side is turned towards the target.