Treating blood, blood products and/or organs under in vitro, and ex vivo condition, involves obtaining blood, blood products and/or organs from human or animal body and removing amyloid beta oligomers from products

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This invention describes a method and kit for removing amyloid beta oligomers from blood, blood products, or organs outside the human or animal body (in vitro or ex vivo). The process may use specific antibodies and other components to purify these biological products, potentially improving their safety for medical use.

Use CasesContent extracted from patent full text and abstract with AI.

• Preparation of blood products for transfusion to reduce risk of amyloid-related complications
• Treatment or purification of donor organs before transplantation
• Research applications to study amyloid beta oligomers in blood or organs
• Potential therapeutic intervention for neurodegenerative conditions by filtering blood outside the body
• Production of safer plasma-derived medications

BenefitsContent extracted from patent full text and abstract with AI.

• Reduces the risk of amyloid beta-related diseases or complications associated with transfusion or transplantation
• May help prevent or slow the progression of neurodegenerative conditions like Alzheimer's disease
• Enhances the safety and quality of blood, plasma, and organ transplants
• Can be applied in both clinical and research environments
• Provides a standardized kit for easy and reproducible removal of harmful oligomers

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Inventors & Applicants

Patent Abstract

Method for treating blood, blood products and/or organs under in vitro, and ex vivo condition, involves obtaining blood, blood products and/or organs from human or animal body and removing amyloid beta oligomers from the products. Independent claims are included for the following: (1) kit for performing the above-cited method which comprises substrate with hydrophobic substances, standard solution, scavenger molecule, probe, substrate with scavenger molecules solutions and buffers; and (2) use of antibodies for removing amyloid beta oligomers comprising (a) retro-inverso sequence of amyloid beta oligomers and/or (b) multimerization domain of amyloid beta oligomers. ACTIVITY : Neuroprotective; Nootropic; Antiparkinsonian; Antidiabetic. No biological data given. MECHANISM OF ACTION : None given.