Device and Method for Effective Non-Invasive Desynchronizing Neurostimulation

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This invention describes a device and method for the effective non-invasive desynchronizing neurostimulation of neurons in the brain and/or spinal cord that exhibit pathologically synchronized and oscillatory activity, characteristic in disorders like Parkinson’s disease, tinnitus, epilepsy, migraine, and others. The system uses weak, controlled stimulation (such as acoustic, visual, tactile, or electrical signals) delivered in a patterned manner, with feedback from monitoring sensors that track neuron activity. When stimulation is not sufficient, the system automatically inserts or extends pauses between stimulation bouts, thereby improving therapeutic effects while reducing side effects and minimizing stimulus intensity.

Use CasesContent extracted from patent full text and abstract with AI.

• Therapeutic treatment of neurological disorders such as Parkinson’s disease, essential tremor, dystonia, or post-stroke complications.
• Management of psychiatric conditions including depression, schizophrenia, obsessive-compulsive disorder, and borderline personality disorder.
• Alleviation of sensory disorders like chronic tinnitus and migraine.
• Treatment of chronic pain syndromes, fibromyalgia, and spasticity.
• Reduction of pathological neural synchronization in epilepsy, Tourette’s syndrome, and other movement disorders.
• Adjunct therapy for neurodevelopmental disorders including autism and ADHD.
• Mitigation of symptoms in disorders like sleep disturbances, irritable bowel syndrome, and cluster headaches.

BenefitsContent extracted from patent full text and abstract with AI.

• Non-invasive design allows for therapy without surgical intervention or implants, improving patient safety and comfort.
• Automatic adjustment and feedback control optimize stimulation effectiveness and minimize side effects.
• Able to deliver long-lasting therapeutic effects with only weak, minimal stimulation, thus reducing risks of over-stimulation and discomfort.
• Applicable to a broad range of neurological and psychiatric conditions marked by abnormal neural synchronization.
• Reduces requirements for high-intensity stimuli, making it suitable for sensitive patient populations (e.g., tinnitus sufferers, migraine patients).
• Closed-loop monitoring ensures treatment is personalized and dynamically adapted to individual patient responses.
• Potential for home use and improved patient adherence owing to the non-invasive, intelligent, and user-friendly system.

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Inventors & Applicants

Patent Abstract

The invention relates to a device for suppressing a pathological synchronous and oscillatory neuron activity, comprising - a non-invasive stimulation unit for stimulation, by way of stimuli, of neurons in the brain and/or spinal cord of the patient, said neurons showing pathologically synchronous and oscillatory neuron activity, and those stimuli being meant to suppress the pathological synchronous and oscillatory neuron activity when administered to the patient, - a measuring unit for recording measurement signals reflecting the neuron activity of the stimulated neurons, and - a control and analysis unit for controlling the stimulation unit and for analyzing the measurement signals. Said control and analysis unit is configured in such a way that it - controls the stimulation unit such that the stimulation unit administers stimuli, - checks the success of stimulation on the basis of the measurement signals recorded in response to the application of the stimuli, and - if the stimulation success is not sufficient, inserts one or more stimulation breaks in the application of the stimuli or extends one or more stimulation breaks, no stimuli which could suppress the pathological synchronous and oscillatory neuron activity being applied during the stimulation breaks.