Method for Modifying a Substrate

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This patent describes a method for modifying the surface of various substrates—including glass, metals, ceramics, polymers, and textiles—by using amino-cellulose derivatives and/or NH2-(organo)polysiloxane derivatives. The process results in a stable, composite material with tailor-made surface properties such as biocompatibility, hydrophilicity/hydrophobicity, and functionality. The modified surfaces can be further functionalized for specific applications by attaching bioactive molecules or nanoparticles. The method is efficient, versatile, and does not require harsh conditions, making it ideal for biomedical, sensor, and nanotechnology uses.

Use CasesContent extracted from patent full text and abstract with AI.

• Surface modification of medical implants to enhance biocompatibility and control cell adhesion.
• Fabrication of biochips and biosensors with customized, functional surfaces for enhanced analyte detection.
• Production of scanning probe microscopy tips with specialized surface features for advanced nanotechnological analysis.
• Creation of drug delivery carriers (e.g., nanoparticles) with tailored surface chemistry for controlled and targeted therapy.
• Functionalization of textiles (e.g., cotton) for biomedical or technical applications such as smart clothing.
• Manufacture of micro- and nano-patterned materials for research in tissue engineering or cell culture studies.
• Customization of surfaces for protein or DNA immobilization in diagnostic devices.

BenefitsContent extracted from patent full text and abstract with AI.

• Enables precise and robust surface modification at the nanoscale, resulting in monolayer or ultra-thin functional coatings.
• Applicable to a wide range of substrate materials (metals, polymers, ceramics, textiles, etc.), providing great versatility.
• Yields composite materials with improved properties such as enhanced mechanical stability, chemical resistance, and biocompatibility.
• Facilitates covalent or non-covalent immobilization of biofunctional molecules, allowing fine-tuned bioactivity and selective responses.
• Supports rapid, simple, and scalable processing methods (e.g., dipping, spin-coating, microcontact printing), even at room temperature.
• Ensures stable attachment of functional layers that resist removal in aqueous or challenging environments, crucial for biomedical devices and sensors.
• Enables custom patterning at the micro- and nanoscale, vital for advanced diagnostics, microfluidics, and sensor technologies.

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Inventors & Applicants

Patent Abstract

The invention concerns a method for modifying a substrate, including the following steps: the substrate is contacted with at least one amino-cellulose derivative and/or with at least one NH2-(organo)polysiloxane derivative; a composite substrate material is formed from the substrate and the amino-cellulose derivative and/or the substrate and the NH2-(organo)polysiloxane derivative. Said method enables a customized structural substrate design to be obtained. The resulting composite substrate material can be used to produce implants, detectors and scanning probe tips.