Device and Method for Single-Cell Analysis of Microorganisms

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This invention provides a device and method for single-cell analysis of microorganisms. The device uses a specialized channel system that allows individual microorganism cells to be introduced and held for analysis, preventing them from escaping through narrow outlets. This design allows for controlled handling and study of single cells in a microfluidic environment.

Use CasesContent extracted from patent full text and abstract with AI.

• Medical diagnostics involving the analysis of single microorganism cells for disease identification
• Pharmaceutical research for testing drug effects on individual microbial cells
• Microbiological research for studying cellular behavior, mutation, or resistance at the single-cell level
• Biotechnology applications, such as selecting or engineering microorganisms with desired traits
• Quality control in fermentation and brewing industries by analyzing specific microbial contaminants

BenefitsContent extracted from patent full text and abstract with AI.

• Enables precise analysis of individual microorganism cells, leading to more detailed and accurate results
• Prevents cross-contamination or loss of cells during analysis due to specialized channel design
• Improves efficiency of single-cell experiments by facilitating better introduction and handling of microorganisms
• Supports advancements in microbiological research and diagnostics with higher resolution
• Can be integrated into automated or high-throughput laboratory systems for faster analysis

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Patent Abstract

The invention relates to a device and a method for single-cell analysis of microorganisms. According to the invention, a device for single-cell analysis of microorganisms is provided with a supply channel (1) and at least one cultivation channel (3) that enables the accommodation of a cell, wherein the cultivation channel (3) opens into a connection channel (5) that is tapered relative to the cultivation channel (3), so that the cell cannot pass through the connection channel (5) and which opens into a drainage channel (6). The liquid stream containing the microorganism is guided through the connection channel (5), which enables better introduction of the microorganism into the cultivation channel (3).