Method for supporting planning, implementation and analysis of clinical studies for e.g. pharmacological data of patient, involves computing value of measurable parameter based on variable that is characteristic for combined compartments

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent describes a computer-aided method for simplifying and simulating clinical study data involving various human body compartments (such as veins, organs, and muscles). It allows researchers to predict how an individual might respond to a substance (like a drug) by modeling and then computationally combining relevant body systems into simplified compartments for analysis.

Use CasesContent extracted from patent full text and abstract with AI.

• Planning and optimizing clinical trials for new drug development
• Simulating patient-specific pharmacological responses before real-world testing
• Analyzing and interpreting results from preclinical or clinical studies
• Supporting precision medicine by predicting individual reactions to treatments
• Reducing the need for extensive animal or human trials through in silico simulations

BenefitsContent extracted from patent full text and abstract with AI.

• Reduces complexity and time in designing and analyzing clinical studies
• Improves prediction accuracy for individual responses to drugs or treatments
• Minimizes the need for large-scale animal or human testing, potentially lowering ethical concerns and costs
• Enables more efficient and targeted development of new therapies
• Supports data-driven decision making in pharmacological research

Technical Classifications (CPCs)

Inventors & Applicants

Patent Abstract

The method involves providing an output simulation environment for prediction of a response of an individual on a substance (15). A simplified simulation environment is generated from the output simulation environment. A value of a measurable parameter representative for the substance is determined. A simplified candidate simulation environment is created by non-rational summary of compartments (1-14) of the output simulation environment. The value of the measurable parameter is computed based on an estimated variable that is characteristic for combined compartments. The compartments are veins, lungs, arteries, brain, heart, thymus, spleen, gastrointestinal organs, liver, kidney, lymph, bone, muscle and remaining organs.