Compositions for Alleviating Gastrointestinal Tract Disorders or Associated Systemic Disorders in Ruminants and Camelids

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This patent introduces feed additives containing specific modulating agents (TRP agonists or antagonists) designed to improve the health and performance of ruminants (such as cows, sheep, goats) and camelids (like camels, llamas). These additives can alleviate gastrointestinal disorders—primarily rumen acidosis and parturient paresis (milk fever)—by optimizing the absorption of key ions (like calcium and ammonium) in the gut, without disturbing beneficial gut microbes. The invention also includes methods for producing such additives, and covers both their use in feed and as veterinary medicines.

Use CasesContent extracted from patent full text and abstract with AI.

• Inclusion in commercial cattle, sheep, goat, or camelid feed to prevent or treat metabolic digestive disorders.
• Supplementation during periods of high risk for rumen acidosis (e.g., dietary transitions, high-starch diets).
• Support in dairy operations to reduce the incidence of parturient paresis (milk fever) around calving.
• Use in intensive livestock farming to improve feed efficiency and animal productivity.
• Reduction of environmental nitrogen emissions by improving nitrogen utilization in the animal.
• Formulation of veterinary medicines to acutely treat gastrointestinal or metabolic crises in ruminants and camelids.

BenefitsContent extracted from patent full text and abstract with AI.

• Prevents or treats serious metabolic disorders like rumen acidosis and milk fever, improving animal welfare and survival.
• Enhances feed conversion efficiency and potentially boosts productivity (milk and meat yields).
• Optimizes calcium and other mineral absorption, reducing the need for problematic high-dose mineral supplements.
• Improves nitrogen utilization, lowering feed costs and environmental pollution from animal waste.
• Does not negatively affect beneficial gut microflora, preserving digestive health and function.
• Flexible and scalable for use in various feed formulations or as targeted medicaments.
• Can be tailored (using specific TRP modulators) for particular species or production scenarios.

Technical Classifications (CPCs)

Inventors & Applicants

Patent Abstract

What are provided are feed additives for the alleviation of gastrointestinal tract disorders and associated systemic disorders in ruminants, methods for producing feed additives, and feeds and feed adjuvants that comprise them. Also described are medicaments for the treatment of diseases which are associated with disorders of the gastrointestinal tract, more particularly rumen acidosis and parturient paresis.