Implantable System for Stimulation of Neurons

Publication: DE102007020305A1
Published: 2008-10-23
Family Size: 2
Granted: No

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent describes an implantable system designed to stimulate neurons in mammals. The core innovation involves using a pressure-sensitive or photosensitive (such as photovoltaic) element to generate an electrical potential, which is then transmitted via a specialized surface. Attached to this surface are neurotransmitters and/or neuromodulators, which can be released or re-captured by the implant when externally stimulated (e.g., by light or pressure), using a molecular linker system. The goal is to mimic or replace lost neuronal signaling pathways, such as in cases of neurodegenerative diseases or sensory organ damage (e.g., retina or cochlea).

Use CasesContent extracted from patent full text and abstract with AI.

  • Retinal implants for patients with degenerative eye diseases (e.g., macular degeneration, retinitis pigmentosa) to restore visual signaling.
  • Cochlear implants for individuals with hearing loss due to damaged synaptic function.
  • Treatment or management of a range of neurological diseases, including epilepsy, neurodegenerative disorders, and neuromotor or neurosensory dysfunctions.
  • Replacement or support for damaged synapses within the central or peripheral nervous system.
  • Artificial neuron interfaces for future brain-machine or neuroprosthetic devices.

BenefitsContent extracted from patent full text and abstract with AI.

  • Allows for finely controlled, stimulus-responsive release (and re-capture) of neurotransmitters or neuromodulators, improving implant longevity and response precision.
  • Reduces or eliminates the need for external electrical current to activate the system, as it can be powered by light or pressure, minimizing heat and potential tissue damage.
  • Enables local, targeted neuronal activation, which can more closely mimic natural synaptic processes compared to traditional electrical stimulation implants.
  • Potential for re-using neurotransmitters through the electrostatic re-capture mechanism, reducing the need for frequent replenishment and increasing system sustainability.
  • Can be customized for different types of neurotransmitters or neuromodulators, allowing adaptation for various neurological conditions or sensory deficits.

Technical Classifications (CPCs)

Main Classifications

Health, Food & Consumer Tech

Sub Classifications

Medical & Vet Science

CPC Codes

A61N1/0543A61N1/36046

Inventors & Applicants

Applicants

Univ Eberhard Karls

Helmholtz Zent B Mat & Energ

Patent Abstract

The present invention relates to an implantable system for exciting neurons in a mammal, having a pressure-sensitive or piezoelectric element for generating an electrical potential. The system comprises a surface conducting the electrical potential, and neurotransmitters and/or neuromodulators that can be released by the implantable system, wherein a linker is provided on the surface, by means of which the neurotransmitters and/or neuromodulators can be fixed on the implantable system and can be electrostatically released by external excitation and optionally fixed again.

Key Information

Publication No.

DE102007020305A1

Family ID

39563539

Publication Date

2008-10-23

Application No.

DE102007020305A

Application Date

2007-04-19

Priority Date

2007-04-19

Granted

No

Possible Cooperation

For further information please contact the transfer office.