Antibacterial Surface Modification for Medical Devices

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent describes a method for modifying the surface of medical devices to make them antibacterial. The invention involves embedding antibacterial metal compounds (like silver, copper, or zinc) into just the outer layer of a biocompatible material (such as silicone or metal), leaving the bulk of the material unaffected. This is achieved using a special process that combines high power pulsed magnetron sputtering (HiPIMS) and plasma-based ion implantation (PBII), resulting in a durable antibacterial surface that inhibits biofilm growth and encrustation without compromising the mechanical properties of the device.

Use CasesContent extracted from patent full text and abstract with AI.

• Urinary tract catheters resistant to bacterial colonization and encrustation.
• Stents with surfaces that inhibit biofilm and mineral deposits, prolonging usability.
• Implantable load-bearing devices (e.g., hip or knee replacements) with enhanced bacterial resistance.
• Long-term indwelling devices such as central venous catheters or endotracheal tubes that benefit from reduced infection risk.
• Orthopedic hardware (plates, screws) where infection control is critical.
• Dental implants or prosthetics requiring durable antibacterial properties.

BenefitsContent extracted from patent full text and abstract with AI.

• Significantly reduces biofilm formation and bacterial colonization on medical devices, lowering infection rates.
• Minimizes surface encrustation, which is a common problem in urinary tract devices, thereby enhancing device longevity.
• Maintains mechanical strength, abrasion resistance, and other physical properties because the bulk material is left unaltered.
• The antibacterial effect is long-lasting and robust against surface scratches, as the dopant is distributed below the surface.
• Reduces the need for systemic antibiotic use and associated risks of resistance and side effects.
• The manufacturing process allows fine control of dopant depth and concentration, making it adaptable for various device types and clinical needs.
• Can be applied to a wide range of biocompatible materials, including polymers and metals.

Technical Classifications (CPCs)

Inventors & Applicants

Patent Abstract

The invention relates to a medical device comprising a biocompatible material having an exposed surface prone to biofilm growth. The biocompatible material comprises a doping of an antibacterial metal compound. A concentration of the doping compound ranges from 1% to 30% (w/w) within an outer layer adjacent to the exposed surface, and is essentially zero within a bulk layer of the biocompatible material.