Device and Method for Treating Living Cells by Means of a Plasma

Publication: WO2011018423A2
Published: 2011-02-17
Family Size: 7
Granted: Yes (2/7)

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent discloses a method and device for treating living cells using plasma (plasmaporation). The invention combines plasma and electric field techniques (such as electroporation) with a system to mix, transport, and deliver active substances, especially in the form of nano- and microparticles, into or onto living tissue. The plasma temporarily opens cell membranes or skin barriers, enabling targeted delivery of substances like drugs directly into cells or tissues, after which the barrier quickly reseals.

Use CasesContent extracted from patent full text and abstract with AI.

  • Targeted cancer therapy by selective delivery of chemotherapy drugs to tumor cells while sparing healthy tissue.
  • Enhanced healing of chronic or post-operative wounds through localized delivery of therapeutic agents and antiseptic effects.
  • Improved transdermal (through skin) delivery of drugs that normally struggle to penetrate the skin barrier.
  • Sterilization and decontamination of medical equipment or implants while simultaneously implanting protective or functional substances.
  • Treatment of skin diseases by enabling efficient and deep-layer application of topical medications.
  • Dental applications such as improved treatment of gum diseases or promotion of bone healing.

BenefitsContent extracted from patent full text and abstract with AI.

  • Enables highly selective and localized delivery of active substances (e.g., drugs), potentially reducing required doses and minimizing side effects.
  • Temporarily opens biological barriers (cell membrane, skin) for rapid uptake of drugs and quickly reseals to prevent infection or contamination.
  • Combines antiseptic/sterilizing effects of plasma with targeted therapy, supporting both infection control and tissue regeneration.
  • Reduces costs by potentially lowering necessary dosages of expensive medications such as chemotherapeutics.
  • Protects sensitive active substances during delivery via encapsulation in nano- or microparticles.
  • Offers a versatile platform applicable to a wide range of medical, dental, and even industrial (e.g., food safety) applications.

Technical Classifications (CPCs)

Main Classifications

Chemistry & Materials Science

Electrical & Electronic Tech

Health, Food & Consumer Tech

Sub Classifications

Biochemistry, Beer & Spirits

Electric Techniques (Other)

Medical & Vet Science

CPC Codes

A61B18/042A61L2/14C12M35/02H05H1/2406H05H1/245H05H1/2465H05H1/42

Inventors & Applicants

Applicants

Leibniz Inst Fuer Plasmaforschung und Technologie E V

Weltmann Klaus-dieter

Von Woedtke Thomas

Lademann Olaf

Patent Abstract

The invention relates to a method and device for treating living cells by means of a plasma (plasmaporation). In addition to conventional devices for generating plasma and generating a field, such as by electroporation, the device comprises devices for mixing and transporting active substances, predominantly in the form of nano and microparticles, for affecting the metabolism of the cells.

Key Information

Publication No.

WO2011018423A2

Family ID

43429591

Publication Date

2011-02-17

Application No.

EP2010061528W

Application Date

2010-08-08

Priority Date

2009-08-11

Granted

Yes (2/7)

Possible Cooperation

For further information please contact the transfer office.