Magnetoactive or Electroactive Composite Material, Its Use and Method for Influencing Biological Cells Attached to the Magnetoactive or Electroactive Composite Material

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent describes a biocompatible composite material—either magnetoactive or electroactive—whose elastic and mechanical properties (like hardness or flexibility) can be reversibly controlled via external magnetic or electric fields. The invention also covers systems and methods for using these materials to influence biological cells that grow or interact with the material's surface, such as by moving them, separating types, or stimulating specific cell behaviors by dynamically altering stiffness or surface properties.

Use CasesContent extracted from patent full text and abstract with AI.

• Customizable cell culture substrates for biological and medical research laboratories.
• Advanced tools for studying cell migration, growth, and differentiation in tissue engineering.
• Dynamic systems for actively separating different cell types or directing cell movement (cell sorting technologies).
• Devices for influencing protein expression and mechanical stimulus responses in cell cultures.
• Regenerative medicine platforms to mimic variable tissue stiffness during in vitro tissue development.
• Instrumentation for drug testing, where variable substrate stiffness simulates different physiological conditions.

BenefitsContent extracted from patent full text and abstract with AI.

• Allows precise, reversible, and real-time control over surface hardness and elasticity, facilitating sophisticated experimental designs.
• Enables local and temporal modulation of cell environment, opening new possibilities for studying cell responses to mechanical stimuli.
• Supports enhanced cell adhesion and compatibility due to biocompatible coatings or modifications.
• Facilitates development of dynamic and adaptive culture systems, closely mimicking the changes seen in natural tissues.
• Improves the ability to direct cell migration, separation, and differentiation in vitro, beneficial for biotech and regenerative medicine.
• Potential to improve reproducibility and relevance of cell-based assays by providing tunable and physiologically appropriate environments.

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Inventors & Applicants

Patent Abstract

The invention relates to biocompatible, soft, magneto-active polymers (MAP), the elasto-mechanical properties of which can be adjusted by a magnetic field. The invention further relates to special magnetic field systems for locally controlling the MAP and moving, separating, controlling, and influencing biological cells on the surface of the MAP material.