Image-capturing Device, System and Method for Capturing Images

Simple SummaryContent extracted from patent full text and abstract with AI.

This invention describes a miniaturized image-capturing device specifically designed for near-field imaging of biological tissue, such as imaging genetic indicators within living tissue. The device integrates a rod-shaped gradient index (GRIN) lens with a digital image sensor into a compact, monolithic unit, eliminating any mechanical separation between these parts. The complete assembly can include components such as a light source, beam splitter, and spacers, all integrated into a single, fixed unit for improved stability, reduced size, and ease of use. The system also includes an evaluation device for processing the captured images, facilitating real-time biological analysis.

Use CasesContent extracted from patent full text and abstract with AI.

• Imaging genetic indicators in living brain tissue for neuroscience research.
• Monitoring cellular activity in freely moving animals during behavioral experiments.
• Integration into head-mounted or implantable systems for long-term biological imaging in lab animals.
• Medical diagnostics requiring minimally invasive imaging of internal or near-surface tissues.
• Continuous monitoring of neural activity in brain-computer interface applications, such as for paralyzed patients.
• Fluorescence microscopy in constrained or mobile settings, such as on small animals or in compact diagnostic devices.

BenefitsContent extracted from patent full text and abstract with AI.

• Significant miniaturization allows imaging in small or mobile subjects with minimal interference.
• Monolithic design improves optical alignment and image stability by eliminating mechanical interfaces and refocusing needs.
• Reduced weight and size compared to conventional setups—beneficial for mobile or implanted applications.
• Integrated construction protects internal optics from dust and contamination, ensuring higher reliability and image quality.
• Supports manufacturing as a disposable (single-use) device, lowering cross-contamination risk and simplifying logistics for experiments or clinics.
• Enhanced user-friendliness by providing a fixed pre-aligned optical path and easy electrical connection.
• Potential for low-cost mass production using wafer-level and 3D-printing manufacturing processes.
• Versatile platform adaptable for various optogenetics and circuit neuroscience explorations.

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Inventors & Applicants

Patent Abstract

The invention relates to an image-capturing device for the miniaturized near-field image capture of biological tissue, in particular for the imaging of genetic indicators. The image-capturing device comprises at least one digital image sensor and an objective lens in the form of a rod-shaped gradient index lens (GRIN), which objective lens is coupled to the digital image sensor for image capture. The objective lens is connected to the digital image sensor to from a monolithic, fixed assembly. There is no mechanical separating interface between the objective lens and the digital image sensor by means of which the digital image sensor can be separated from the objective lens by the user. The invention further relates to a system for the miniaturized near-field image capture of biological tissue, said system comprising an image-capturing device of this type and an evaluation device connected to the image-capturing device.