Microelectrode Array for an Electrocorticogram (ecog)

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This patent describes a microelectrode array designed for electrocorticography (ECoG) that integrates both electrical sensors (electrodes) for measuring brain waves and optical stimulation units (such as LEDs) for directly stimulating targeted brain regions with light. The innovation lies in the compact, flexible arrangement where both electrical measurement and optical stimulation components are integrated onto a single thin, flexible substrate, allowing precise and coordinated manipulation and recording of brain activity.

Use CasesContent extracted from patent full text and abstract with AI.

• Neuroscience research involving brain mapping and functional studies.
• Epilepsy monitoring and identification of epileptogenic brain zones prior to surgery.
• Optogenetics experiments, enabling targeted light-based stimulation of genetically modified neurons while simultaneously recording electrical activity.
• Development of advanced brain-computer interfaces (BCIs) for prosthetic control or assistive technologies.
• Closed-loop neurostimulation therapies for neurological or psychiatric disorders.
• Drug delivery studies requiring simultaneous electrical and optical access to neural tissue.

BenefitsContent extracted from patent full text and abstract with AI.

• Combines electrical recording and optical stimulation in a single, compact implantable device, reducing surgical complexity and space requirements.
• Allows high-precision, localized stimulation of brain tissue with light, alongside high-fidelity measurement of resulting neural activity.
• Reduces the risk of tissue damage or inflammation compared to separate, bulkier devices; enhances safety with integrated sensors (like temperature and light intensity monitoring).
• Flexible substrate material conforms to the brain's surface, improving signal quality and patient comfort.
• Wireless powering and communication options reduce infection risk and improve patient mobility post-implantation.
• Supports advanced experimental designs, such as closed-loop stimulation based on real-time recorded data, and mapping of functional brain topographies (e.g., tonotopy, retinotopy).

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Inventors & Applicants

Patent Abstract

The invention relates to a microelectrode array (1), comprising a plurality of electrodes (2) for electrically measuring brain waves and an integrated optical stimulation unit for stimulating brain regions (11) by means of optical signals, wherein the stimulation unit has one or more electrical light sources (3).