Biomarkers for determining physical stress in humans and animals, a method for determining physical stress, and a kit for carrying out the method

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent describes a biomarker—specifically, soluble Syndecan-4 or similar heparan sulfate proteoglycans—whose concentration in blood is used to determine the physical exertion or load experienced by humans and animals during physical activity or sports. The invention also covers a method and a kit for measuring this biomarker, providing an objective way to assess training state, exertion, or overtraining, overcoming limitations associated with traditional markers like lactate.

Use CasesContent extracted from patent full text and abstract with AI.

• Monitoring training intensity and recovery in athletes to prevent overtraining and optimize performance.
• Assessing physical exertion and strain in animals, such as racehorses or working dogs.
• Medical or rehabilitation settings to objectively evaluate patient exertion and tailor activity plans.
• Sports science research to study physiological responses to different training regimens.
• Team sports or military training for individualized monitoring of load and recovery needs.
• Development and commercialization of diagnostic kits for use in sports medicine and veterinary practice.

BenefitsContent extracted from patent full text and abstract with AI.

• Provides an objective, reliable measure of physical exertion beyond traditional methods like lactate measurements.
• Allows early detection of overtraining or insufficient recovery, potentially preventing injuries and reducing recovery times.
• Applicable to both humans and animals; broad utility across sports and veterinary applications.
• The biomarker has a slower return to baseline than lactate, making it suitable for post-exertion analysis.
• Facilitates individualized training and recovery optimization.
• Kit format enables practical, ex vivo testing using established laboratory techniques such as ELISA.

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Patent Abstract

The invention relates to a biomarker for determining the physical exertion of humans and animals in sport and a method for determining the physical exertion in sport, and a kit for carrying out the method. According to the invention, use is made of a biomarker of the group of heparan sulfate proteoglycans, in particular of the family of the syndecan family, the concentration of which in the blood allows conclusions to be drawn about the physical exertion of the human or animal after physical activity. The method is also suitable for determining the training state of athletes.