myotwin GmbH
myotwin GmbH is a biotech company specializing in human-relevant, preclinical testing systems for cardiovascular drug development using engineered human heart tissues and AI-powered digital twins.
About
myotwin GmbH is a Germany-based biotech company that develops innovative preclinical testing platforms for cardiovascular drug discovery. Their proprietary TrinityScreen platform enables simultaneous measurement of contraction force, tissue stiffness, calcium dynamics, and electrical activity in engineered human heart tissue. As a next step, myotwin is developing myoAI, a digital twin of the heart muscle that leverages artificial intelligence to predict drug efficacy and toxicity. The company's mission is to accelerate, de-risk, and humanize drug development, enabling faster, more reliable, and animal-free solutions for cardiovascular diseases. myotwin is a spin-off from the University Medical Center Göttingen and works closely with research institutions, industry partners, and investors.
Products & Services
- TrinityScreen platform for simultaneous high-content measurement (contraction force, tissue stiffness, calcium dynamics, electrical activity) in human engineered heart tissues
- myoAI digital heart twin for AI-based drug efficacy and toxicity prediction
- Preclinical assay services for cardiovascular drug candidates (including efficacy, cardiotoxicity, and biodistribution testing)
- Custom generation and characterization of human heart tissues (from iPSC-derived cell lines or client-provided lines)
- Assay planning consultation
- Disease modeling with engineered cardiac tissues
Use Cases & Case Studies
- Preclinical screening of cardiovascular drugs for efficacy, cardiotoxicity, and biodistribution in human-relevant systems
- AI-powered predictions of drug response on human cardiac tissues
- Reducing animal testing by replacing traditional animal models with human engineered tissues
- Disease modeling for cardiovascular research
Partnerships & Collaborations
- Joint AI-based Cardiac Bodies project with IndiScale GmbH (data management company)
- Collaboration with Life Science Valley Göttingen
- Project partnerships fostered at BIO-Europe, MPS World Summit, and other biotech events
Awards & Recognition
- EXIST Research Transfer program recipient (German government innovation grant)
- HTI funding program award from State of Lower Saxony