Reference Material for Solid-State Analysis, Method for Producing the Reference Material, and Use of the Reference Material

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This invention describes a novel reference material for solid-state analysis, consisting of at least one metal acetylacetonate complex homogeneously embedded in an acrylate-based polymer matrix. The material serves as a calibration standard for analytical methods targeting solid samples. The invention also covers a solvent-free manufacturing method to achieve highly uniform distribution of one or several target elements (such as Fe, Cr, La, Zn, etc.) within the polymer matrix, making it particularly suitable for the calibration of spatially resolved analytical techniques.

Use CasesContent extracted from patent full text and abstract with AI.

• Calibration of solid-state analytical instruments (e.g., X-ray fluorescence, ICP-MS, LIBS, SIMS)
• Quality control in laboratories analyzing solid organic or biological samples
• Development of customized standards for analyzing specific element combinations in solid matrices
• Reference materials for deep-profile analysis and confocal micro X-ray fluorescence (CXRF)
• Calibration standards for elemental mapping in medical and biological research
• Use in vacuum-based analytical methods where conventional standards may fail due to solvent volatilization

BenefitsContent extracted from patent full text and abstract with AI.

• Enables creation of highly homogeneous, tailor-made reference materials for a wide range of elements and concentrations
• Solvent-free production reduces contamination and enhances stability, especially in vacuum conditions
• Prevents drying and concentration shifts common in gelatine or water-based standards
• Flexible formulation allows matching of matrix properties to the target sample (e.g., tissue-like for biological samples)
• Stackable (layered) standards for depth-resolved calibration, unlike oil-based reference materials
• Simple, scalable, and reproducible manufacturing process with readily available starting materials
• Enables precise calibration and increases confidence in quantitative solid-state analysis results

Technical Classifications (CPCs)

Inventors & Applicants

Patent Abstract

The invention relates to a reference material for solid-state analytics, the reference material comprising at least one acetylacetonate of an element in an acrylate-based polymer.