Biocompatible and Bioactive Bone Substitute Material

Publication: WO2012059201A1
Published: 2012-05-10
Family Size: 1
Granted: No

Simple SummaryContent extracted from patent full text and abstract with AI.

This invention presents a novel method for producing bone substitute materials that are both biocompatible and bioactive. The process involves using supercritical fluids (like carbon dioxide) to synthesize bioactive inorganic compounds (such as calcium carbonate or strontium carbonate) within a polymer matrix, leading to a material with improved homogeneity, porosity, and the ability to integrate bioactive substances. The resulting materials can support bone regeneration and healing, and can be tailored for specific medical applications.

Use CasesContent extracted from patent full text and abstract with AI.

  • Bone defect repair and filling in orthopedic surgeries
  • Treatment of osteoporosis-related fractures or bone loss
  • Scaffold for bone tissue engineering and regenerative medicine
  • Implants for repairing or replacing damaged bone due to trauma or disease
  • Bone graft material for dental, craniofacial, or maxillofacial reconstruction
  • Drug delivery systems for local antibiotic or growth factor release in infected or compromised bone
  • Minimally invasive repair of bone defects using injectable viscous forms

BenefitsContent extracted from patent full text and abstract with AI.

  • Enhanced biocompatibility, minimizing risk of immune response or rejection
  • Bioactivity supports and stimulates bone growth, leading to better integration with natural bone
  • Controlled porosity and pore interconnectivity, resembling natural bone structure and promoting cell infiltration
  • Ability to incorporate therapeutic agents (antibiotics, growth factors, etc.) for multifunctional implants
  • Customizable mechanical properties and degradation rates, suitable for a wide range of clinical needs
  • Potential for producing materials in sterile, ready-to-use forms, improving safety and logistics
  • Minimizes risk of disease transmission and supply limitations compared to donor bone grafts

Technical Classifications (CPCs)

Main Classifications

Health, Food & Consumer Tech

Sub Classifications

Medical & Vet Science

CPC Codes

A61L27/3821A61L27/46

Inventors & Applicants

Applicants

Univ Berlin Tech

Zehbe Rolf-dieter

Patent Abstract

The present invention relates to a method for producing a biocompatible and/or bioactive material, to an apparatus for producing said material, to said material itself and to its uses in medical applications.

Key Information

Publication No.

WO2012059201A1

Family ID

43770535

Publication Date

2012-05-10

Application No.

EP2011005456W

Application Date

2011-10-28

Priority Date

2010-11-02

Granted

No

Possible Cooperation

For further information please contact the transfer office.