Method and Device for Producing a Three-Dimensional, Multi-Cell Object

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This patent describes a method and device for producing three-dimensional, multi-cellular objects, such as artificial organs, by using light to build up layers of polymerized, cell-containing materials. The process involves photopolymerizable liquids, which can contain various types of biological cells, and uses focused light to precisely create complex 3D structures, including different materials and cell types in various regions and layers. The technology allows for automated and highly reproducible creation of intricate biological models, including healthy or diseased organ analogues, for research and potential medical applications.

Use CasesContent extracted from patent full text and abstract with AI.

• Production of artificial organs for transplantation or implantation
• Generation of complex organ or tissue models for pharmaceutical drug testing
• Creation of customized disease models (e.g., cancer, diabetes) for research
• Fabrication of miniaturized multi-cellular structures for educational or diagnostic purposes
• Development of organ-on-chip systems for studying organ function or disease progression
• Manufacture of pregnancy models for reproductive research
• Use in personalized medicine to create patient-specific tissues or organoids

BenefitsContent extracted from patent full text and abstract with AI.

• Allows for high-precision and reproducible 3D structuring of biological materials
• Enables integration of multiple cell types and materials within a single object
• Improves the creation of complex tissue and organ models compared to traditional 2D culture or manual methods
• Reduces variability and increases reliability of testing and analysis in pharmaceutical development
• Fully automatable process reduces labor and time requirements
• Facilitates generation of both healthy and disease-mimicking structures for advanced biomedical research
• Supports customized and scalable production, including parallel processing of different models

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Patent Abstract

The invention relates to a method for producing a three-dimensional, multi-cell object, in which polymerized structures are produced in layers by the irradiation of light radiation. To this end, use is made of photopolymerizable liquids which at least partly comprise biological cells. The invention also relates to a device for carrying out such a method and to the use of this device for producing an artificial organ.