Microfluidic Device with Hierarchical Membrane for Separating Cells from Blood

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This patent describes a microfluidic device equipped with a specially structured substrate and a microporous, hierarchically structured membrane. The device is designed to separate organic matter or cells from surrounding biological fluids, such as blood. The invention also covers a method of manufacturing the device by forming fluid channels in the substrate and integrating the microporous membrane.

Use CasesContent extracted from patent full text and abstract with AI.

• Separation of blood components (e.g., extracting plasma or serum from whole blood) in diagnostic equipment
• Processing of biological samples in medical laboratories for disease screening or monitoring
• Cell sorting or cell isolation applications in research and clinical laboratories
• Preparation of samples for molecular diagnostics, such as DNA/RNA extraction from blood
• Point-of-care testing devices for rapid blood analysis

BenefitsContent extracted from patent full text and abstract with AI.

• Efficient and selective separation of organic matter or cells from complex biological fluids
• Potential for miniaturization and integration into portable, point-of-care devices
• Reduced sample handling and contamination risk due to integrated closed-system design
• Scalable manufacturing process for producing consistent and precise microfluidic devices
• Improved reliability and accuracy in biological testing and diagnostics

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Inventors & Applicants

Patent Abstract

A microfluidic device (1) comprises a structured substrate (2a,2b), which includes a fluid receiving and/or transporting structure (3a,3b). A microporous membrane (5) is also included, where the microporous membrane is connected with the structured substrate for incorporation or transport of a fluid. The microporous membrane is a microfilter with a hierarchical structure. An independent claim is also included for a method for producing microfluidic device, which includes: (A) forming receiving and/or transporting structure in substrate; and (B) applying and joining microporous membrane with the structured substrate.