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AlveoliX AG

AlveoliX AG develops and commercializes advanced organs-on-chip systems for preclinical research and drug development, with a focus on lung models.

BiotechnologyMedical DevicesPharmaceutical ResearchOrgan-on-ChipIn Vitro ModelsPersonalized MedicinePreclinical Testing
Founded: 2019

About

AlveoliX AG is a Swiss biotechnology company specializing in the development and commercialization of organs-on-chip platforms that accurately recreate the microenvironment of human tissues. Their main focus is on lung-on-chip technology, which simulates breathing mechanics and physiological conditions to provide more predictive and translational models for drug discovery, disease modeling, and safety testing. The company's mission is to make organs-on-chip the new standard for preclinical decision-making, aiming to reduce animal testing and accelerate drug development by providing better, safer, and more personalized data from bench to clinic.

Products & Services

  • AXLung-on-Chip System
  • AXBarrier-on-Chip System
  • AXBiomodels (incl. AX12 breathing lung-on-chip platforms)
  • Custom organ-on-chip solutions
  • Human-relevant in vitro models for lung and other organs
  • Advanced inhalation models
  • Precision drug testing services

Use Cases & Case Studies

  • Lung disease and inflammation modeling (e.g., ARDS, IPF, COVID-19)
  • Inhalation toxicity testing and preclinical drug screening
  • Modeling vascular leak syndrome from cancer immunotherapy
  • Nanoparticle and aerosol inhalation studies
  • Studying fibrosis and pulmonary effects of viral infection (SARS-CoV-2)
  • Assessing anti-inflammatory drug response in lung pathologies
  • Wound healing and tissue regeneration assays with physiological stretch

Partnerships & Collaborations

  • Collaborations with University of Bern (Unibern)
  • Inselspital (Bern University Hospital)
  • Sitem StartUp Club
  • Medtech Hub
  • Helmholtz-Institute for Pharmaceutical Research Saarland
  • ARTORG Center for Biomedical Engineering Research
  • Eurostars (EU Horizon 2020)
  • Innosuisse (Swiss Innovation Agency)
  • Ypsomed
  • Gebert Rüf Stiftung

Awards & Recognition

  • Winner of the Swiss Medtech Award (SMT Award) 2022
  • Nominated for the CTI Swiss Medtech Award
  • Featured in Swiss Venture Capital Report 2021

Contact Information