
Synendos Therapeutics AG
Synendos Therapeutics AG is a clinical-stage biotech company developing first-in-class endocannabinoid modulators for the treatment of neuropsychiatric and central nervous system (CNS) disorders.
About
Synendos Therapeutics AG is a Swiss clinical-stage neuroscience company focused on developing innovative and potentially breakthrough therapies for neuropsychiatric and CNS disorders. Utilizing over a decade of research from the University of Bern, the company develops first-in-class selective endocannabinoid reuptake inhibitors (SERIs), targeting a novel mechanism in the endocannabinoid system (ECS) to restore natural brain function. The lead candidate, SYT-510, is aimed at treating diseases with high unmet medical need such as post-traumatic stress disorder (PTSD). Synendos' approach is supported by strong preclinical and clinical evidence, a robust patent portfolio, and significant grant and venture capital funding.
Products & Services
- SYT-510 (lead drug candidate, selective endocannabinoid reuptake inhibitor for CNS disorders)
- Development of second-generation SERIs (Selective Endocannabinoid Reuptake Inhibitors)
- Research and development of drugs for neuropsychiatric and CNS disorders
Use Cases & Case Studies
- Restoring endocannabinoid balance in CNS disorders such as PTSD, anxiety and mood-related disorders
- Novel oral therapeutics with improved safety profile for patients with stress and mood-related CNS diseases
Partnerships & Collaborations
- University of Bern (spin-out origin, ongoing access to ECS expertise)
- BaseLaunch (venture accelerator and incubator support)
- NCCR TransCure (collaboration in drug transporter research)
- Collaboration with various CROs for medicinal chemistry development
Awards & Recognition
- EMA Clinical Trial Authorisation for SYT-510 (2024)
- Swiss Economic Award 2025 finalist (Deeptech / Life Sciences)
- Bio-Neuroscience Award for 'Best Pitch' (2025)
- Top 100 Swiss Startups (2021, 2022)
- Top 100 Swiss Startup Public Voting Award 2021 (Biotech)
- Innosuisse Certificate
- Venture Leaders Life Science 2019
- Venture Kick Stage III winner (2019)
- BaseLaunch Phases I and II awardee
- >>venture>> competition healthcare finalist
Contact Information
Certifications & Compliance
- Innosuisse Certificate
- EMA Clinical Trial Authorisation