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Combioxin SA

Combioxin SA is a Swiss clinical-stage biotechnology company developing first-in-class life-saving drugs for severe infections.

BiotechnologyPharmaceuticalsHealthcareInfectious DiseasesDrug DevelopmentLife Sciences
Founded: 2015

About

Combioxin SA is a Swiss-based clinical-stage biotechnology company founded in 2015 and focused on the development of disruptive, first-in-class treatments for severe and resistant infections. Their lead product, CAL02, is a novel liposomal anti-toxin agent designed to neutralize virulence effectors from pathogens that cause organ failure and lethal complications in severe infections, particularly community-acquired bacterial pneumonia. CAL02 works as a broad-spectrum, non-antibiotic drug that can be used alongside standard antibiotic treatments, actively addressing both drug-sensitive and drug-resistant infections. The company engages in international partnerships for commercialization and is committed to transforming the standard of care in critical care infections globally.

Products & Services

  • CAL02 – a first-in-class liposomal anti-toxin agent for severe community-acquired bacterial pneumonia and severe infections

Use Cases & Case Studies

  • CAL02 as adjunctive therapy to antibiotics for patients with severe community-acquired bacterial pneumonia in intensive care
  • CAL02 use to prevent organ failure and reduce ICU stay in patients with severe pneumonia

Partnerships & Collaborations

  • Worldwide licensing agreement with Eagle Pharmaceuticals for the commercial rights to CAL02

Awards & Recognition

  • FDA Fast-Track Designation for CAL02
  • Qualified Infectious Disease Product (QIDP) designation by FDA
  • Clinical trial results ranked as 'a medical breakthrough' in The Lancet Infectious Diseases

Contact Information