Planar high-speed molecule sequencer

Simple SummaryContent extracted from patent full text and abstract with AI.

This invention describes a planar, high-speed molecule sequencer that uses nanochannels and electrodes to quickly and accurately analyze molecules such as DNA. Unlike traditional nanopore sequencing devices, this sequencer aligns molecules in a flat channel and uses specially mounted electrodes for electrical interrogation, improving efficiency and the ability to process longer molecules. Multiple such sequencers can be fabricated together on a single chip for parallel analysis.

Use CasesContent extracted from patent full text and abstract with AI.

• Rapid DNA sequencing for medical diagnostics
• Genome research and analysis
• High-throughput drug discovery
• Pathogen detection and biosurveillance
• Forensic science and identification
• Agricultural biotechnology and plant genomics

BenefitsContent extracted from patent full text and abstract with AI.

• Enables faster molecule sequencing compared to traditional nanopore devices
• Allows processing of longer molecules, improving sequencing of complex samples
• Eases large-scale and parallel fabrication for high-throughput operations
• Provides more precise control and alignment of molecules for higher accuracy
• Integration with existing chip manufacturing methods lowers costs and enhances scalability

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Patent Abstract

A molecule sequencer uses a planar nanochannel for aligning molecules to flow past impedance interrogation electrodes mounted across the channel for rapid sequencing. The electrodes may be fixed to the channel walls to provide improved registration by co-fabrication with the channel. Extended channel length over normally used nanopores can provide improved control of longer molecules and allow parallel sequencers to be readily fabricated on a single substrate.