Substance for the Prophylaxis and Treatment of Infections Caused by Influenza Viruses

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent discloses the use of tiliroside, a plant-derived flavonoid, and its derivatives for the prevention and treatment of influenza virus infections. The invention shows that tiliroside effectively inhibits influenza viruses, including strains resistant to existing antiviral drugs like Oseltamivir, by blocking the virus's entry and release from host cells. The patent covers pharmaceutical compositions containing tiliroside for various routes of administration, including oral, topical, rectal, or vaginal forms.

Use CasesContent extracted from patent full text and abstract with AI.

• Prophylactic treatment (prevention) of influenza in at-risk populations such as healthcare workers, elderly, or immunocompromised individuals.
• Therapeutic treatment of active influenza infections, especially those caused by drug-resistant strains.
• Development of antiviral formulations (tablets, capsules, mouth sprays, ointments) for over-the-counter or prescription use against influenza.
• Emergency use during influenza outbreaks where resistance to current antivirals has emerged.
• Adjunct therapy with other antiviral agents to improve overall treatment outcomes against influenza infections.

BenefitsContent extracted from patent full text and abstract with AI.

• Effective against multiple influenza virus strains, including those resistant to standard antivirals like Oseltamivir.
• Novel mechanism of action—blocks early stages of viral entry and release, potentially reducing viral load significantly.
• Lower risk of side effects compared to existing influenza antivirals due to high specificity and efficacy at low concentrations.
• Broad range of pharmaceutical formulations and administration routes enabling flexible and patient-friendly dosage forms.
• Potential for both prevention and treatment, expanding utility from seasonal flu outbreaks to pandemic preparedness.

Technical Classifications (CPCs)

Inventors & Applicants

Patent Abstract

The invention relates to tiliroside or derivatives thereof for use in the prevention and/or treatment of viral infections by influenza viruses, a composition containing tiliroside or derivatives thereof, and uses and methods associated therewith.