Flavonoide-type Compounds Bearing an O-Rhamnosyl Residue

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent describes novel flavonoid-type compounds that contain an O-rhamnosyl residue (a type of sugar molecule attached via an oxygen bond) at specific positions on the flavonoid structure that were previously difficult or impossible to synthesize. These new compounds exhibit improved water solubility, stability, and bioavailability compared to traditional flavonoids, and they display enhanced pharmacological, cosmetic, and flavor-modulating activities. The invention also details ways to produce these compounds biotechnologically, making industrial-scale production feasible.

Use CasesContent extracted from patent full text and abstract with AI.

• Pharmaceuticals for treatment or prevention of diseases such as skin diseases, allergies, autoimmune diseases, cardiovascular diseases, lung diseases, asthma, infectious diseases (bacterial, viral, or parasitic), metabolic syndrome, cancer, Alzheimer's disease, arthritis, dysfunctional hair growth, dysfunctional wound healing, or diabetes.
• Cosmetic formulations for anti-aging, anti-wrinkle, sun protection, anti-pollution, and skin/hair health enhancement.
• Functional foods, beverages, and dietary supplements to deliver health-promoting ingredients such as antioxidants and anti-inflammatories.
• Animal feed additives to improve animal health and combat infection or metabolic disorders.
• Flavor enhancement and modulation in food, drinks, or pharmaceuticals (e.g., reducing bitterness or enhancing sweetness).

BenefitsContent extracted from patent full text and abstract with AI.

• Greatly improved water solubility and stability of flavonoid compounds compared to traditional forms, allowing higher doses and greater efficacy in various applications.
• Enhanced bioavailability, meaning the compounds are better absorbed and utilized in the body.
• Improved safety profile and reduced cytotoxicity in human cell cultures at higher concentrations.
• Multi-functional pharmacological activities, including antioxidant, anti-inflammatory, antibacterial, antiviral, antifungal, anti-cancer, and metabolic regulatory effects.
• Support for skin health, including promoting collagen synthesis and wound healing, reducing wrinkles, and protecting against environmental pollutants and UV radiation.
• Modulation of taste properties, allowing for better-tasting functional foods and pharmaceuticals.
• Biotechnological production methods enable scalable and cost-effective manufacture, overcoming the limitations of natural abundance and chemical synthesis.

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Inventors & Applicants

Patent Abstract

The present invention relates to compounds of formula (I) These compounds are useful in the treatment of many diseases such as a skin disease, an allergy, an autoimmune disease, a cardiovascular disease, a lung disease, asthma, a bacterial, viral or parasitic disease, metabolic syndrome, cancer, Alzheimer's disease or diabetes and are furthermore useful in the preparation of cosmetics and for use in food and animal feed.