System and Apparatus for Nanopore Sequencing

Simple SummaryContent extracted from patent full text and abstract with AI.

This invention relates to a nanopore sequencing system that uses a piezoelectric substrate to precisely control the size of the nanopore through electrical stimulation. By adjusting the nanopore opening with electrical signals, the system enables highly sensitive and customizable biological measurements, such as DNA or protein sequencing.

Use CasesContent extracted from patent full text and abstract with AI.

• Real-time DNA sequencing for genomics research
• Protein analysis in clinical diagnostics
• Environmental monitoring for detecting microorganisms
• Rapid identification of pathogens in medical settings
• Research in molecular biology and personalized medicine

BenefitsContent extracted from patent full text and abstract with AI.

• Allows for highly sensitive and precise measurements of biological molecules
• Enables dynamic control and adjustment of nanopore size for various applications
• Improves sequencing accuracy and throughput by optimizing nanopore conditions
• Potentially reduces costs and complexity compared to fixed nanopore devices
• Supports a wide range of biological measurements and assays

Technical Classifications (CPCs)

Inventors & Applicants

Patent Abstract

A piezoelectric substrate having a nanopore opening that separates two reservoirs of conductive fluid may provide for sensitive biological measurements by allowing control of the size of the nanopore according to piezoelectric stimulation of the substrate. Multiple embodiments are provided of monolithic piezoelectric substrates and nanopores for this purpose as well as a control system for controlling the nanopore dimensions electrically using AC or DC waveforms.