Suspension of Nanoscale, Organic Particles and Process for Production Thereof

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent describes a novel method for creating suspensions of nanoscale organic particles, such as pharmaceutical active ingredients, in water using water-soluble transition metal salts (like zirconium or hafnium salts) to stabilize the suspension. The method allows for stable, non-agglomerating nanoparticles without needing conventional organic stabilizers (like surfactants or emulsifiers), and produces particles with controlled and narrow size distributions (smaller than 350 nm, often <150 nm). It also covers converting these suspensions into dry forms suitable for pharmaceutical formulations, cosmetics, coatings, and agricultural products.

Use CasesContent extracted from patent full text and abstract with AI.

• Improving the bioavailability of poorly water-soluble drugs by formulating them as stable nanoscale suspensions for oral or parenteral administration.
• Developing cosmetic products with stable, nanoparticulate active ingredients or dyes for enhanced delivery or appearance.
• Producing dry powders containing stable, nanoscale drug particles for use in tablets, capsules, or reconstitution as suspensions.
• Formulating stable nanoparticle suspensions for crop protection agents (pesticides, herbicides) for enhanced efficacy and stability.
• Improving the performance and durability of paints, coatings, and surface treatments by incorporating organic nanoparticles stabilized via this method.

BenefitsContent extracted from patent full text and abstract with AI.

• Significant increase in stability of nanoscale organic particles in water without the need for traditional organic stabilizers, reducing formulation complexity and potential toxicity.
• Enhanced control over particle size and distribution, leading to more predictable and optimized drug delivery and performance in end products.
• Increased bioavailability of poorly soluble pharmaceutical compounds, potentially improving their effectiveness and reducing required dosages.
• Versatility in application, covering pharmaceuticals, cosmetics, agriculture, and material coatings.
• Simplified process for manufacturing and isolating nanoscale organic particles, with possible scalability for industrial production.

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Inventors & Applicants

Patent Abstract

The invention relates to a suspension of nanoscale, organic particles, to a process for the production thereof, to the use of a water-soluble transition metal salt for stabilizing a suspension of nanoscale, organic particles, and to the use of the suspension, and to a dry preparation comprising nanoscale, organic particles.