Method for producing a liquid sample for analysis by use of radiation

Simple SummaryContent extracted from patent full text and abstract with AI.

This invention introduces a method and device for preparing a liquid sample for analysis using radiation (such as X-rays), where at least two solutions are mixed and form a single drop that hangs from a specifically shaped area. The flow of solutions is stopped once the drop forms, minimizing contact with any surfaces. The drop is then directly irradiated for analysis, which allows more accurate measurements and reduces errors caused by traditional sample chamber surfaces.

Use CasesContent extracted from patent full text and abstract with AI.

• Real-time analysis of rapid chemical reactions using X-ray, UV, IR, or visible light spectroscopy.
• Structural analysis of chemical, biological, or pharmaceutical samples with minimal contamination from container surfaces.
• Investigation of reaction kinetics in fast biochemical or enzymatic processes.
• Screening of reaction products in drug discovery or material science research.
• High-throughput repeated measurements in academic and industrial laboratories.

BenefitsContent extracted from patent full text and abstract with AI.

• Significantly reduces or eliminates interference from sample chamber walls, improving measurement accuracy.
• Allows direct analysis of the sample drop by radiation, minimizing surface-induced artifacts or reactions.
• Compatible with fast, repetitive measurements (up to 10 Hz), enhancing high-throughput workflows.
• Adaptable to various types of radiation, broadening the range of analytical techniques.
• Minimizes contamination risk and sample loss due to reduced sample-surface interactions.
• Enables the study of reactions and compounds sensitive to surface effects or adsorption.

Technical Classifications (CPCs)

Inventors & Applicants

Patent Abstract

The invention concerns a method for producing a liquid sample for analysis by use of radiation (18), wherein the sample is produced in stopped-flow technique, wherein at least two solutions are forced into an area (10), wherein the area (10) is orientated and shaped such that a drop (17) hanging at the area (10) can be formed, wherein flow of the solutions into the area (10) is stopped when the drop (17) has formed and is hanging at the area (10).