Method for 2D-3D Registration, Computing Device and Computer Program

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This invention presents a method, computing system, and software program for aligning (registering) 2D x-ray images with 3D image datasets, such as those from CT or MRI scans, of a specific region in a patient. The method uses reference structures and advanced image processing to accurately track movements between the times the 2D and 3D images were captured, improving the accuracy of the alignment.

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• Assisting surgeons during minimally invasive procedures by matching real-time x-ray images with preoperative 3D scans to guide instruments.
• Improving tumor localization in radiation therapy by aligning 2D intraoperative x-ray images with 3D planning images.
• Enhancing diagnostic imaging workflows, such as comparing past 3D scans with current 2D x-rays for tracking disease progression.
• Supporting robotic surgery systems that require precise spatial referencing of patient anatomy.

BenefitsContent extracted from patent full text and abstract with AI.

• Increases the accuracy of matching 2D x-ray images with 3D datasets, reducing error due to patient movement or anatomical changes.
• Enables better guidance for image-assisted medical procedures, leading to improved safety and outcomes.
• Potentially reduces procedure time and radiation exposure by minimizing the need for additional imaging.
• Facilitates more personalized and adaptive treatments, especially in fields like radiation therapy and interventional radiology.

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Patent Abstract

A method for registering a three-dimensional image data record of a target region of a patient with a two-dimensional x-ray image is provided. The method includes selecting at least one rigid reference structure with an associated contour; establishing a two-dimensional gradient x-ray image and a three-dimensional gradient data record of the image data record; finding a neighborhood in the gradient x-ray image from a plurality of neighborhoods extending about test points for a plurality of contour points; establishing local two-dimensional displacement information by comparison of the contour points with the associated comparison points; establishing movement parameters of a three-dimensional movement model describing a movement of the target region between recording of the image data record and the x-ray image from the local two-dimensional displacement information; and establishing a registration transformation describing the registration by correcting the test transformation based on the movement parameters.