4d Cone Beam Ct Using Deformable Registration

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This patent describes a method and system for improving 4D cone beam computed tomography (CBCT) imaging by using deformable image registration techniques. It reconstructs high-quality volumetric images of body regions that move due to physiological cycles (like breathing or heartbeat). The technique combines and modifies projection images from multiple phases or bins of the physiological cycle, using deformation or registration information, to create more accurate and less noisy volumetric images.

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• Improved imaging for radiation therapy planning, accounting for patient respiratory or cardiac motion.
• Enhanced diagnostic imaging for moving organs, such as the lungs or heart, in clinical CT and CBCT imaging systems.
• Motion-compensated 4D imaging to create dynamic visualizations for disease diagnosis, treatment monitoring, or intervention planning.
• Integration into radiology software to reduce noise and artifacts in images acquired from patients who cannot hold their breath during scans.
• Use in adaptive radiotherapy, where changes in patient anatomy over time must be precisely tracked.

BenefitsContent extracted from patent full text and abstract with AI.

• Produces higher quality and clearer 3D/4D images even with patient motion, leading to better diagnosis and treatment planning.
• Reduces image noise without increasing the radiation dose to the patient, improving patient safety.
• Allows use of all collected data (from multiple physiological states), maximizing information content for each reconstructed image.
• Enables accurate visualization of moving targets, crucial for precise radiation targeting or diagnosis.
• Provides flexible image reconstruction for arbitrary phases or amplitude ranges, supporting personalized and adaptive medical procedures.

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Patent Abstract

A method of obtaining a volumetric image includes obtaining a plurality of volumetric images, the volumetric images generated using respective sets of projection images, wherein the volumetric images and the respective sets of projection images correspond with different respective bins for a physiological cycle, and determining an additional volumetric image using one or more of the projection images from each of the sets that correspond with the different respective bins for the physiological cycle, wherein the act of determining the additional volumetric image is performed using a processor.