Wound Dressing Comprising Polymer Fibers

Simple SummaryContent extracted from patent full text and abstract with AI.

This invention describes a wound dressing consisting of a supporting frame made from a biocompatible or biodegradable polymer, spanned by one or more layers of organic polymer fibers that are preferably aligned and produced using electrospinning. The design maintains the beneficial structure and porosity of aligned fibers, which supports healing, while the frame provides mechanical stability and enables fixation to tissue by suturing or stapling. The dressing is especially suited for eye or corneal treatments, can be customized in shape, and may include multiple fiber layers in various orientations for enhanced strength.

Use CasesContent extracted from patent full text and abstract with AI.

• Treatment of ocular surface injuries, particularly corneal wounds or surgeries.
• General wound coverage where stable, bioactive dressings are needed (e.g., skin, oral, or mucosal wounds).
• Grafts or scaffolds in tissue engineering for promoting regeneration and healing.
• Temporary or permanent wound coverings that biodegrade without the need for surgical removal.
• Delivery of drugs, growth factors, or antimicrobials thanks to integration of active agents in the fibers or an embedded hydrogel.
• Veterinary wound care, especially for animals with challenging wound locations or those prone to mechanical stress on dressings.

BenefitsContent extracted from patent full text and abstract with AI.

• Improved mechanical stability of the wound dressing, reducing the risk of displacement during healing or from body/tissue movement.
• Preservation of parallel fiber alignment for enhanced contact guidance and support of cell growth/healing, especially critical in corneal applications.
• Maintained porosity enables gas and fluid exchange, creating a supportive healing environment.
• Biocompatible and/or biodegradable materials reduce risk of rejection and eliminate the need for removal after healing.
• Customizable shapes and anatomical fit, facilitating treatment of curved or complex surfaces like the cornea.
• Enhanced handling and fixation thanks to the frame, which can be sutured or stapled for robust placement.
• Ability to incorporate drugs or bioactive agents directly into the dressing for controlled release at the wound site.

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Inventors & Applicants

Patent Abstract

The present invention relates to a wound dressing, comprising a frame, which comprises at least one organic frame polymer and at least one layer of fibers spanning the frame, the fibers comprising at least one organic fiber polymer. Furthermore, the invention relates to a process for manufacturing a wound dressing of the preceding claims comprising the steps of generating at least one layer of polymer fibers comprising an organic fiber polymer by electrospinning, providing the frame which comprises an organic frame polymer, and depositing at least one layers of aligned polymer fibers on the frame.