6'-sialyllactose for Use in the Treatment of Hearing Loss

Simple SummaryContent extracted from patent full text and abstract with AI.

This invention relates to the use of 6'-sialyllactose, a sugar found in human milk, for the prevention and treatment of hearing loss and hearing loss-associated tinnitus. The patent demonstrates that 6'-sialyllactose can protect against or slow down hearing loss caused by factors such as aging, noise exposure, and certain medications, particularly by preserving sensory hair cells and neurons in the inner ear. The compound can be administered as part of a pharmaceutical or nutritional composition and may offer both curative and protective effects.

Use CasesContent extracted from patent full text and abstract with AI.

• Prevention or treatment of age-related hearing loss in adults, especially the elderly population.
• Protecting workers in loud environments (e.g., factories, construction sites, military) from noise-induced hearing loss.
• Reducing the risk or severity of hearing loss in patients receiving ototoxic medications like certain antibiotics or chemotherapy agents.
• Addressing hearing loss-associated tinnitus, especially in patients with early signs of sensorineural hearing impairment.
• Inclusion of 6'-sialyllactose in nutritional supplements or functional foods to support auditory health.
• Adjunct therapy in otolaryngology to stabilize or improve hearing in at-risk patients.

BenefitsContent extracted from patent full text and abstract with AI.

• Provides a novel, non-invasive therapy for hearing loss and tinnitus, with potential preventive and therapeutic applications.
• Demonstrates protective effects at the cellular level by reducing the loss of hair cells and neurons in the inner ear.
• May reduce or delay the onset of permanent and often irreversible sensorineural hearing loss.
• Shows effectiveness against various types of acquired non-infectious hearing loss, including that induced by noise, aging, or drugs.
• Can be incorporated into both pharmaceutical and nutritional compositions, offering versatile application routes (oral, injectable, etc.).
• Potential for fewer side effects, as 6'-sialyllactose is a naturally occurring component in human milk and considered safe for consumption.

Technical Classifications (CPCs)

Inventors & Applicants

Patent Abstract

The present invention relates to 6'-sialyllactose and/or pharmaceutically acceptable salts thereof for use in the treatment of a disease selected from hearing loss and hearing loss-associated tinnitus.