Innovation Portfolio
University of Bonn
Excellence university with renowned research in mathematics, physics, economics, and life sciences. Strong focus on sustainability research, artificial intelligence, and matter research clusters.
227
Patents
630
Inventors
28
Active Spin-offs
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Patent Portfolio
Analysis of our organization's intellectual property assets
Patents by Technology Area
Portfolio Highlights
Total Patents
227
Recent Patent Publications (2024 & 2025)
21
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Patent Portfolio
Featured Technologies
Discover our latest patented technologies
CONSTRUCT COMPRISING mRNA-STRAND AND RETINOIC ACID-INDUCIBLE GENE I (RIG-I)-LIGAND(S), PHARMACEUTICAL COMPOSITION AND KIT COMPRISING THE SAME
The present invention relates to a construct comprising a mRNA-strand, and at least one, preferably at least two, retinoic acid-inducible gene I (RIG-l)-ligand(s) comprising a) a nucleic acid sequence being capable of binding to RIG-1, b) a linker moiety L comprising 3 to 24 main chain atoms, and c) a single-stranded nucleic acid sequence capable of hybridizing to at least one nucleic acid sequence of the mRNA-strand. The present invention further provides said construct for use as a medicament and/or for use as a vaccine, a pharmaceutical composition and kit comprising said construct, said construct for use in a method of treatment or prevention of a disease, the use of said construct as a vaccine and/or an immune adjuvant, said construct for use in a method of inducing an immune response as well as a method of treating and a method of inducing an immune response.
Use of Cellobiofructose and Production Method Thereof
The present invention relates to the use of cellobiofructose (CBF) as a dietary fiber and/or prebiotic component in food products, food product additives, nutraceuticals and/or beverages or for increasing the growth of probiotic microorganisms. The invention further relates to CBF and compositions containing it for use in the prevention and/or treatment of obesity, constipation, high cholesterol, diabetes, hypertension, and/or heart disease. The invention further encompasses a method for the (recombinant) production of cellobiofructose (CBF), as described herein, using a polypeptide having levansucrase activity which comprises or consists of a polypeptide having at least 80 % sequence identity to the amino acid sequence set forth in SEQ ID NO: 1.
Means and Methods for Linking Genetic Perturbations or the Expression of a Gene or Rna of Interest with Phenotypes of Cells
The present invention relates to a method for linking the genetic perturbations of individual cells within a cell population to the phenotype of the individual cells. The present invention also relates to a method for linking the expression of a gene or RNA of interest in individual cells within a cell population to the phenotype of the individual cells. The present invention furthermore relates to a nucleic acid molecule comprising in 5'-3' direction a U6 promoter, a gRNA and a T7 promoter reverse complement.
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