Coenzyme Q10 Aerosol

Simple SummaryContent extracted from patent full text and abstract with AI.

This patent describes a formulation and method for preparing Coenzyme Q10 as a nano-sized aerosol that can be administered by inhalation. The Coenzyme Q10 is converted into a stable dry powder, which can be easily reconstituted to form a nano-emulsion suitable for aerosolization through inhalers or nebulizers. This enables direct and efficient delivery of CoQ10 to the lungs for local or systemic therapeutic effects.

Use CasesContent extracted from patent full text and abstract with AI.

• Treatment of respiratory diseases such as asthma, COPD, chronic bronchitis, and cystic fibrosis by delivering CoQ10 directly to the lungs.
• Adjunct therapy for lung cancer and other respiratory system cancers, providing antioxidant support and potentially synergy with existing cancer treatments.
• Supportive therapy for cardiovascular diseases where inhaled CoQ10 could reach systemic circulation quickly.
• Potential treatment option for metabolic disorders such as obesity by enhancing energy metabolism in the body.
• A delivery route for CoQ10 supplementation in patients unable to tolerate oral administration or needing higher bioavailability.
• Research tool for studying pulmonary delivery of lipophilic antioxidants and drugs.

BenefitsContent extracted from patent full text and abstract with AI.

• Enhanced bioavailability of CoQ10 via pulmonary delivery, bypassing poor oral absorption and rapid systemic elimination.
• Particle size optimization (nanometer range) allows for efficient deep lung delivery and absorption.
• Enables local treatment of lung diseases with high concentrations of CoQ10 directly at the site of pathology.
• Dry powder formulation is stable for storage and can be easily reconstituted for use, improving shelf-life and convenience.
• Formulation avoids the need for heat or harsh processing, preserving CoQ10 integrity and potency.
• Flexible administration via existing aerosol delivery devices – jet, ultrasonic, pressurized, or vibrating plate nebulizers.
• Reduces need for invasive routes (such as intravenous administration), improving patient compliance.

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Inventors & Applicants

Patent Abstract

The present invention provides a formulation of Coenzyme Q10 that can be re-dispersed from a stable dry powder to formulation to yield a nano dispersion that can be readily aerosolized for inhalation.